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Minimap2 is a versatile sequence alignment program that aligns DNA or mRNA
sequences against a large reference database. Typical use cases include:
(1) mapping PacBio or Oxford Nanopore genomic reads to the human genome
(2) finding overlaps between long reads with error rate up to ~15%
(3) splice-aware alignment of PacBio Iso-Seq or Nanopore cDNA or Direct RNA
readsagainst a reference genome
(4) aligning Illumina single- or paired-end reads
(5) assembly-to-assembly alignment
(6) full-genome alignment between two closely related species with divergence
below ~15%